{
  "id": 10983940,
  "title": "Induction of hysteretic chromatin states by CRISPRa reveals locus-specific encoding of transcriptional memory",
  "url": "https://urgent.news/2026/09/30/induction-of-hysteretic-chromatin-states-by-crispra-reveals-locus",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-30T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.29.755468v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Transcriptional memory is a phenomenon that allows cells to 'remember' prior stimulatory history, which can alter subsequent gene expression patterns and shape development, immunity, and disease. Although various epigenetic adaptations have been implicated, it remains unclear whether the mechanics of transcription alone are sufficient to install durable memory independently of complex activation…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}