{
  "id": 10976236,
  "title": "Ligand binding remodels the oligomeric state and active site of Klebsiella pneumoniae azoreductase",
  "url": "https://urgent.news/2026/09/30/ligand-binding-remodels-the-oligomeric-state-and-active-site-of",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-30T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.29.755508v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Azo dyes are widespread in the environment, and humans ingest a range of these dyes present in food and drugs. The human gut microbiome significantly impacts the fate of ingested azo dyes primarily through the reduction of the azo bond (R-N=N-R'). Flavin-dependent azoreductases have been considered the key enzymatic drivers of this process. To challenge this paradigm, we constructed a sequence…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 2,
    "also_reported_by": [
      {
        "outlet": "bioRxiv",
        "title": "The iron-binding siderophore enterobactin is required for the response of multi-drug resistant Klebsiella pneumoniae to zinc limitation",
        "url": "https://urgent.news/2026/09/28/the-iron-binding-siderophore-enterobactin-is-required-for-the",
        "published": "2026-09-28T00:00:00.000Z"
      }
    ]
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}