{
  "id": 10808407,
  "title": "MIMOSA: Guiding De Novo Antibody Design with Natural Interaction Fingerprints",
  "url": "https://urgent.news/2026/09/29/mimosa-guiding-de-novo-antibody-design-with-natural-interaction",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-29T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.24.753155v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "De novo antibody design promises to transform therapeutic antibody and nanobody discovery. Yet, success remains inconsistent across targets, with generative models often yielding no experimentally validated binders. Here we introduce MIMOSA (MIMic-Oriented Structural Antibody generation), a model-agnostic, inference-time framework that constrains diffusion-based antibody design pipelines to…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}