{
  "id": 10719122,
  "title": "SpaReg: sparsity-based 3D reconstruction of tissue microenvironments at native resolution across morphological and spatial molecular modalities",
  "url": "https://urgent.news/2026/09/29/spareg-sparsity-based-3d-reconstruction-of-tissue-microenvironments",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-29T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.28.754175v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Tissue microenvironments comprise cellular and acellular components whose three-dimensional (3D) architecture guides disease fate. Direct imaging of intact specimens by light-sheet and multiphoton microscopy, and computational reconstruction from serial sections, have established that 3D spatial context reveals cell and tissue organization inaccessible at single planes. Computational…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}