{
  "id": 10504381,
  "title": "Jefferies cuts Kodiak Sciences stock price target on valuation review",
  "url": "https://urgent.news/2026/09/28/jefferies-cuts-kodiak-sciences-stock-price-target-on-valuation-review",
  "topic": "finance",
  "section": "Finance & Markets",
  "published": "2026-09-28T18:18:48.000Z",
  "source": {
    "name": "Investing.com",
    "slug": "investing-com",
    "url": "https://www.investing.com/news/analyst-ratings/jefferies-cuts-kodiak-sciences-stock-price-target-on-valuation-review-93CH-4920995"
  },
  "original_language": "en",
  "account": "Jefferies adjusted its price target for Kodiak Sciences Inc. (KOD) to $112, down from $156, while keeping its Buy rating. The company's stock has risen 105% in the past year, reaching $90.25, but analysts believe it may be overvalued. The DAYBREAK trial for Zenkuda showed aflibercept-like efficacy, clean safety, and Q24W dosing in 54% of patients under strict retreatment criteria, positioning it as a potential best-in-class treatment. However, the company's Phase 3 trials for KSI-501 and ALTO, which test the IL-6 thesis, remain crucial for commercial execution. Kodiak Sciences reported a loss of $1.05 per share in Q2, surpassing analyst estimates, primarily due to increased R&D expenses for PEAK, PINNACLE, and Phase 3 studies. Goldman Sachs rated Kodiak Sciences as Neutral with a $36 target, while H.C. Wainwright maintained a Buy rating with a $58 target, emphasizing the importance of the Phase 3 DAYBREAK trial focusing on wet AMD treatment-naïve patients.",
  "summary": null,
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 4,
    "also_reported_by": [
      {
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        "url": "https://urgent.news/2026/09/28/nvidias-150b-buyback-fails-to-keep-chip-stocks-buoyant",
        "published": "2026-09-28T15:38:18.000Z"
      },
      {
        "outlet": "CNBC",
        "title": "Stocks making the biggest moves midday: MongoDB, Boeing, Kodiak Sciences, Roblox, Nvidia & more",
        "url": "https://urgent.news/2026/09/28/stocks-making-the-biggest-moves-midday-mongodb-boeing-kodiak-sciences",
        "published": "2026-09-28T17:02:18.000Z"
      },
      {
        "outlet": "Investing.com",
        "title": "Nvidia at $230: ceiling test or breakout in the making",
        "url": "https://urgent.news/2026/09/28/nvidia-at-230-ceiling-test-or-breakout-in-the-making",
        "published": "2026-09-28T18:24:43.000Z"
      }
    ]
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}